As per the research, published within the journal Cell, recovery from COVID-19 also as vaccination may offer only incomplete protection against these mutant forms
Variant sorts of the novel coronavirus which were first reported in South Africa and Brazil are less efficiently inhibited by antibodies from recovered patients and vaccinated individuals, a replacement study confirms.
According to the research, published within the journal Cell, recovery from COVID-19 also as vaccination may offer only incomplete protection against these mutant virus forms.
"This is worrisome because the speedy spread of variants which may not be efficiently restrained by antibodies could undermine our current vaccination strategy," said Stefan Pohlmann, a co-author of the study from the German Primate Center in Gottingen.
These virus variants have mutations within the spike protein, the structure on the surface of the virus that's liable for attachment to host cells, the researchers said.
For the virus to enter a cell, they said it must first attach to the host cell surface using its spike protein, which is found on the viral envelope. The spike protein is additionally the target for antibody therapies and vaccines aimed toward preventing the virus from replicating within the body, the researchers added.
Based on the research, the scientists said an antibody used for COVID-19 therapy didn't inhibit the South African and Brazilian coronavirus variants: B.1.351 and P.1.
"Moreover, these variants were less well inhibited by antibodies from convalescent or vaccinated individuals, they partially bypassed the neutralizing effect of the antibodies," said Jan Munch, another co-author of the study.
The study saw that vaccination or recovery from COVID-19 may offer weakened protection from SARS-CoV-2 variants B.1.351 and P.1.
"Our findings tell that it's important to limit the expanse of the virus the maximum amount as possible until widespread vaccination is possible. Otherwise, we risk the emergence of the latest variants that can't be effectively controlled by the currently available vaccines," said Markus Hoffmann, first author of the study.
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